Exopolysaccharide production by <i>Lactobacillus plantarum</i> T10 is responsible for the probiotic activity in enhancing intestinal barrier function <i>in vitro</i> and <i>in vivo</i>
Ting Tao, Li Zhang, Tianfei Yu, Jiaxue Ma, Shuang Lu, Jing Ren, Xiangyu Li, Xiaohua Guo
Abstract
T10 led to the alleviation of dextran sulfate sodium-induced colitis by reducing intestinal damage and enhancing the intestinal barrier function in mice. The EPS is classified as a heteropolysaccharide with an average molecular weight of 23.0 kDa. It is primarily composed of mannose, glucose, and ribose. These findings have practical implications for the targeted screening of lactobacilli used in the production of probiotics and postbiotics with strain-specific features of exopolysaccharides.
Topics & Concepts
ProbioticLactobacillus plantarumMicrobiologyIn vitroIn vivoLactobacillusBiologyBacteriaChemistryLactic acidBiotechnologyBiochemistryGeneticsProbiotics and Fermented FoodsGut microbiota and healthHelicobacter pylori-related gastroenterology studies