The structure and function of YTHDF epitranscriptomic m6A readers
Vilbert Sikorski, Simona Selberg, Maciej Łałowski, Mati Karelson, Esko Kankuri
Abstract
A-RNA fate become clear. We provide an updated understanding of the modes of action of DF1-DF3 and review their structures to unlock insights into drug design approaches for DF paralog-selective inhibition.
Topics & Concepts
Function (biology)PsychologyComputational biologyBiologyCell biologyRNA modifications and cancerPeptidase Inhibition and AnalysisHVDC Systems and Fault Protection