Lysosomal targeting of autophagosomes by the TECPR domain of TECPR2
Milana Fraiberg, Bat-Chen Tamim-Yecheskel, Kamilya Kokabi, Nemanja Subic, Gali Heimer, Franziska Eck, Karsten Nalbach, Christian Behrends, Bruria Ben‐Zeev, Oren Shatz, Zvulun Elazar
Abstract
HOPS: homotypic fusion and vacuole protein sorting; LIR: LC3-interacting region; SPG49: spastic paraplegia type 49; STX17: syntaxin 17; TECPR2: tectonin beta-propeller repeat containing 2; VAMP8: vesicle associated membrane protein 8.
Topics & Concepts
BiologyAutophagyCell biologyDomain (mathematical analysis)MitophagyLysosomeNeuroscienceBiochemistryEnzymeApoptosisMathematical analysisMathematicsAutophagy in Disease and TherapyAdenosine and Purinergic SignalingCalcium signaling and nucleotide metabolism