Visible light-induced phosphine-catalyzed perfluoroalkylation of indoles
Xiuhui Gao, Xuling Pan, Peiyi Wang, Zhichao Jin
Abstract
A photo-induced, catalytic PPh 3 -promoted perfluoroalkylation reaction of indole molecules is developed to give perfluoroalkylated products in moderate to excellent yields, of which 13 F-containing indoles exhibited good antibacterial activities.
Topics & Concepts
ChemistryIndole testPhosphineCatalysisCombinatorial chemistryOrganic chemistryPhotochemistryFluorine in Organic ChemistryInorganic Fluorides and Related CompoundsRadical Photochemical Reactions