The use of hydroxychloroquine as a systemic treatment in erosive lichen planus of the vulva and vagina
H. A. B. Vermeer, Hanan Rashid, Martha D. Esajas, J Oldhoff, Barbara Horváth
Abstract
Erosive lichen planus affecting the vulva and vagina (ELPV) is a rare inflammatory skin disease, presenting with painful erosions and severe scarring.1 The disease course is persistent and often refractory to treatment: up to 45% patients do not experience remission with topical treatments, while evidence for systemic treatments remains scarce.2 Hydroxychloroquine (HCQ) is frequently used in daily practice as a first choice systemic therapy.3 However, little evidence is available on HCQ for ELPV.2 The aim of this study was to analyse the effectiveness and safety of HCQ in ELPV.
Topics & Concepts
VulvaHydroxychloroquineVaginaDermatologyMedicineSurgeryPathologyCoronavirus disease 2019 (COVID-19)DiseaseInfectious disease (medical specialty)Oral Health Pathology and TreatmentNail Diseases and TreatmentsAutoimmune Bullous Skin Diseases