Litcius/Paper detail

How should the advancement of large language models affect the practice of science?

Marcel Binz, Stephan Alaniz, Adina L. Roskies, Balázs Aczél, Carl T. Bergstrom, Colin Allen, Daniel J. Schad, Dirk U. Wulff, Jevin D. West, Qiong Zhang, Richard M. Shiffrin, Samuel J. Gershman, Vencislav Popov, Emily M. Bender, Marco Marelli, Matthew Botvinick, Zeynep Akata, Eric Schulz

2025Proceedings of the National Academy of Sciences51 citationsDOIOpen Access PDF

Abstract

Large language models (LLMs) are being increasingly incorporated into scientific workflows. However, we have yet to fully grasp the implications of this integration. How should the advancement of large language models affect the practice of science? For this opinion piece, we have invited four diverse groups of scientists to reflect on this query, sharing their perspectives and engaging in debate. Schulz et al. make the argument that working with LLMs is not fundamentally different from working with human collaborators, while Bender et al. argue that LLMs are often misused and overhyped, and that their limitations warrant a focus on more specialized, easily interpretable tools. Marelli et al. emphasize the importance of transparent attribution and responsible use of LLMs. Finally, Botvinick and Gershman advocate that humans should retain responsibility for determining the scientific roadmap. To facilitate the discussion, the four perspectives are complemented with a response from each group. By putting these different perspectives in conversation, we aim to bring attention to important considerations within the academic community regarding the adoption of LLMs and their impact on both current and future scientific practices.

Topics & Concepts

Argument (complex analysis)Affect (linguistics)ConversationUnintended consequencesEngineering ethicsPsychologyPolitical sciencePublic relationsSociologyEpistemologyEngineeringMedicineLawCommunicationPhilosophyInternal medicineTopic ModelingMachine Learning in Materials ScienceComputational and Text Analysis Methods