Activity-based selection for enhanced base editor mutational scanning
E L Kaplan, Ryan J. Steger, Spencer T. Shah, Laura M Drepanos, Audrey L Griffith, Ganna Reint, John G. Doench
Topics & Concepts
Selection (genetic algorithm)Computational biologyBiologyBase (topology)Modular designComputer scienceGenome editingInterrogationNoise (video)Knowledge baseCRISPRHuman diseaseNegative selectionImage editingBackground selectionGenomeHuman genomeGeneticsResolution (logic)Artificial intelligenceBase pairMutationMachine learningBasis (linear algebra)CRISPR and Genetic EngineeringRNA and protein synthesis mechanismsEvolution and Genetic Dynamics