Litcius/Paper detail

CLN3 is required for the clearance of glycerophosphodiesters from lysosomes

Nouf N. Laqtom, Wentao Dong, Uche N. Medoh, Andrew L. Cangelosi, Vimisha Dharamdasani, Sze Ham Chan, Tenzin Kunchok, Caroline A. Lewis, Ivonne Heinze, Rachel Tang, Christian Grimm, An Dang, Forbes D. Porter, Alessandro Ori‬‬, David M. Sabatini, Monther Abu-Remaileh

2022Nature140 citationsDOIOpen Access PDF

Topics & Concepts

Metabolic clearance rateChemistryInternal medicineMedicinePharmacokineticsLysosomal Storage Disorders ResearchCellular transport and secretionCalcium signaling and nucleotide metabolism