A validated LC-MS/MS method for determination of antiviral prodrug molnupiravir in human plasma and its application for a pharmacokinetic modeling study in healthy Egyptian volunteers
Amira S. Gouda, Hoda M. Marzouk, Mamdouh R. Rezk, Ahmed Salem, Mosaad I Morsi, Eman G. Nouman, Youmna M. Abdallah, Ahmed Y. Hassan, Ahmed M. Abdel‐Megied
Topics & Concepts
ChemistryChromatographyTriple quadrupole mass spectrometerProtein precipitationPharmacokineticsBioanalysisSelected reaction monitoringAnalyteCmaxActive metaboliteTandem mass spectrometryMass spectrometryMetaboliteAnalytical Chemistry (journal)PharmacologyBiochemistryMedicineSARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testingPlant Virus Research Studies