TREM-2 Drives Development of Multiple Sclerosis by Promoting Pathogenic Th17 Polarization
Siying Qu, Shengfeng Hu, Huiting Xu, Yongjian Wu, Siqi Ming, Xiaoxia Zhan, Cheng Wang, Xi Huang
Topics & Concepts
Experimental autoimmune encephalomyelitisSTAT proteinRAR-related orphan receptor gammaMultiple sclerosisImmunologyConditional gene knockoutCell biologyEncephalomyelitisBiologyImmune systemSTAT3ChemistrySignal transductionPhenotypeFOXP3BiochemistryGeneInflammation biomarkers and pathwaysNeuroinflammation and Neurodegeneration Mechanisms