Okicamelliaside targets the N-terminal chaperone pocket of HSP90 disrupts the chaperone protein interaction of HSP90-CDC37 and exerts antitumor activity
Chuanjing Cheng, Kaixin Liu, Man Zhang, Fu-kui Shen, Lili Ye, Wenbo Wu, Xiaotao Hou, Erwei Hao, Yuanyuan Hou, Gang Bai
Topics & Concepts
Hsp90CDC37Chaperone (clinical)Heat shock proteinGeldanamycinChemistryBiochemistryBiologyMedicineGenePathologyHeat shock proteins researchEndoplasmic Reticulum Stress and DiseaseATP Synthase and ATPases Research