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The mutational landscape of human somatic and germline cells

Luiza Moore, Alex Cagan, Tim Coorens, Matthew D. C. Neville, Rashesh Sanghvi, Mathijs A. Sanders, Thomas R. W. Oliver, Daniel Leongamornlert, Peter Ellis, Ayesha Noorani, Thomas J. Mitchell, Timothy Butler, Yvette Hooks, Anne Y. Warren, Mette Jorgensen, Kevin J. Dawson, Andrew Menzies, Laura P. O’Neill, Calli Latimer, Mabel Teng, Ruben van Boxtel, Christine A. Iacobuzio–Donahue, Iñigo Martincorena, Rakesh Heer, Peter J. Campbell, Rebecca C. Fitzgerald, Michael R. Stratton, Raheleh Rahbari

2021Nature390 citationsDOI

Topics & Concepts

GermlineSomatic cellBiologySomaGermline mutationMutation rateGeneticsPopulationMutationGeneSociologyDemographyNeuroscienceCancer Genomics and DiagnosticsEvolution and Genetic DynamicsCRISPR and Genetic Engineering
The mutational landscape of human somatic and germline cells | Litcius