The Intrinsically Disordered Proteins MLLT3 (AF9) and MLLT1 (ENL) – Multimodal Transcriptional Switches With Roles in Normal Hematopoiesis, MLL Fusion Leukemia, and Kidney Cancer
Ashish Kabra, John H. Bushweller
Topics & Concepts
Fusion proteinMyeloid leukemiaCell biologyHistoneBiologyCancer researchChemistryGeneGeneticsRecombinant DNARNA Research and SplicingCancer-related gene regulationGenomics and Chromatin Dynamics