Pervasive biases in proxy genome-wide association studies based on parental history of Alzheimer’s disease
Yuchang Wu, Zhongxuan Sun, Qinwen Zheng, Jiacheng Miao, Stephen Dorn, Shubhabrata Mukherjee, Jason M. Fletcher, Qiongshi Lu
Topics & Concepts
BiologyProxy (statistics)Genome-wide association studyDiseaseAssociation (psychology)Genetic associationAlzheimer's diseaseGeneticsEvolutionary biologyGeneSingle-nucleotide polymorphismGenotypePsychologyInternal medicineComputer sciencePsychotherapistMachine learningMedicineGenetic Associations and EpidemiologyLiver Disease Diagnosis and TreatmentEpigenetics and DNA Methylation