Litcius/Paper detail

The impact of cryo-EM on determining allosteric modulator-bound structures of G protein-coupled receptors

Liudi Zhang, Jesse I. Mobbs, Lauren T. May, Alisa Glukhova, David M. Thal

2023Current Opinion in Structural Biology31 citationsDOI

Topics & Concepts

Allosteric regulationG protein-coupled receptorDrug discoverySmall moleculeComputational biologyAllosteric modulatorLigand (biochemistry)Structural biologyBinding siteBiologyReceptorChemistryBiophysicsNanotechnologyBioinformaticsBiochemistryMaterials scienceReceptor Mechanisms and SignalingMass Spectrometry Techniques and ApplicationsMonoclonal and Polyclonal Antibodies Research
The impact of cryo-EM on determining allosteric modulator-bound structures of G protein-coupled receptors | Litcius