Litcius/Paper detail

Palladium-catalyzed one-pot cycloaddition reactions of thioureas with 3<i>H</i>-indol-3-ones generated<i>in situ</i>from 2-alkynyl arylazides: rapid and efficient access to imidazoloindolines

Ping Li, Boyu Zhu, Yao Xu, Zhiqiang Zhou, Guiwen Hu, Fan Yang, Shijie Xu, Xiaoxiang Zhang

2020Organic Chemistry Frontiers21 citationsDOI

Abstract

An efficient palladium-catalyzed one-pot synthesis of imidazoloindolines from 2-alkynyl arylazides under mild reaction conditions has been described.

Topics & Concepts

ChemistryPalladiumCatalysisCycloadditionIn situCombinatorial chemistryReaction conditionsOrganic chemistryMedicinal chemistryCatalytic C–H Functionalization MethodsSynthesis and Catalytic ReactionsSulfur-Based Synthesis Techniques