Electrospun based functional scaffolds for biomedical engineering: A review
Laldinthari Suamte, Punuri Jayasekhar Babu
Abstract
Tissue engineering (TE) has made significant strides and progress in the development of functional biomaterials. Among different techniques that has been adopted, electrospinning is a versatile and widely adopted fabrication process for creating biomedical scaffolds. These intricate 3-dimensional matrices play a crucial role in various tissue engineering applications . Electrospinning is a technique commonly utilized in TE as it produces ultrafine fibres through an electric field to draw polymer solutions , melting them into thin fibres. These fibres form a scaffold with a high surface area-to-volume ratio, making them ideal for tissue engineering. This review discusses the various biomedical applications of electrospun scaffolds in different fields, such as dentistry, bone regeneration, wound healing , bone marrow regeneration, vascular tissue engineering, corneal regeneration and liver tissue engineering. Also, this review highlights the multiple parameters affecting the design of the scaffolds for tissue regeneration. As research in this field continues, electrospun scaffolds are likely to become more reliable and effective. Their ability to mimic natural tissue structures and promote cellular interactions positions them as a promising avenue for future biomedical advancements.