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Astragaloside IV antagonizes M2 phenotype macrophage polarization-evoked ovarian cancer cell malignant progression by suppressing the HMGB1–TLR4 axis

Xue Wang, Shouyang Gao, Liyou Song, Ming Liu, Ziqian Sun, JunBao Liu

2020Molecular Immunology53 citationsDOI

Topics & Concepts

Ovarian cancerCancer researchCD163Macrophage polarizationTumor microenvironmentHMGB1Cancer cellBiologyM2 MacrophageOvarian tumorMacrophageImmunologyCancerInternal medicineMedicineIn vitroInflammationBiochemistryTumor cellsImmune cells in cancerImmune Response and InflammationCancer Immunotherapy and Biomarkers
Astragaloside IV antagonizes M2 phenotype macrophage polarization-evoked ovarian cancer cell malignant progression by suppressing the HMGB1–TLR4 axis | Litcius