A Multiplex PCR and DNA-Sequencing Workflow on Serum for the Diagnosis and Species Identification for Invasive Aspergillosis and Mucormycosis
Sébastien Imbert, L. Portejoie, Elliot Pfister, Brigitte Tauzin, Mathilde Revers, J. Uthurriague, M. Hernandez-Grande, M-E Lafon, Charlotte Jubert, Nahéma Issa, P-Y Dumas, Laurence Delhaès
Abstract
There has been significant increase in the use of molecular tools for the diagnosis of invasive aspergillosis (IA) and mucormycosis. However, their range of detection may be too limited as species diversity and coinfections are increasing.
Topics & Concepts
MucoralesMucormycosisBiologyAspergillosisAspergillusAspergillus fumigatusMicrobiologyPolymerase chain reactionPathologyMedicineImmunologyGeneticsGeneAntifungal resistance and susceptibilityFungal Infections and StudiesPlant Pathogens and Fungal Diseases