Gout-associated monosodium urate crystal-induced necrosis is independent of NLRP3 activity but can be suppressed by combined inhibitors for multiple signaling pathways
Chun-Su Zhong, Bo Zeng, Jia-hao Qiu, Lihui Xu, Mei-Yan Zhong, Yuanting Huang, Rong Xu, Siying Liu, Qingbing Zha, Bo Hu, Dong‐Yun Ouyang, Xian‐Hui He
Topics & Concepts
NecroptosisPyroptosisInflammasomeNecrosisGoutProgrammed cell deathNALP3ChemistryPharmacologyTumor necrosis factor alphaAllopurinolApoptosisMedicineCell biologyBiochemistryImmunologyBiologyInternal medicineReceptorInflammasome and immune disordersGout, Hyperuricemia, Uric AcidViral Infections and Vectors