Inhibition of ERK1/2 phosphorylation attenuates spinal cord injury induced astrocyte activation and inflammation through negatively regulating aquaporin-4 in rats
Jian Li, Zhiqiang Jia, Qiangqiang Zhang, Junyu Dai, Jundong Kong, Zhongkai Fan, Gang Li
Topics & Concepts
AstrocyteAquaporin 4Proinflammatory cytokineGlial fibrillary acidic proteinMAPK/ERK pathwaySpinal cord injuryInternal medicineEndocrinologyInflammationSpinal cordChemistryKinaseBiologyMedicineCell biologyNeuroscienceCentral nervous systemImmunohistochemistrySpinal Cord Injury ResearchNeurogenesis and neuroplasticity mechanismsNerve injury and regeneration