Mechanism of ferroptosis in hypoxia-induced pulmonary vascular remodeling in hypoxia pulmonary hypertension: a study based on the ACE2-Ang-(1–7)-Mas axis
Asimuguli Abudukeremu, Ainiwaer Aikemu, Tao Yang, Lei Fang, Daliya Shanahati, Yiliyaer Nijiati
Topics & Concepts
Hypoxia (environmental)Pulmonary hypertensionPulmonary arteryGPX4Cancer researchVasodilationAngiotensin-converting enzyme 2Downregulation and upregulationMedicineLungVascular resistancePharmacologyOxidative stressInternal medicineBiologyChemistryGlutathione peroxidaseHemodynamicsDiseaseSuperoxide dismutaseOxygenBiochemistryCoronavirus disease 2019 (COVID-19)GeneOrganic chemistryInfectious disease (medical specialty)Pulmonary Hypertension Research and TreatmentsRenin-Angiotensin System StudiesMicroRNA in disease regulation