<p>Ketamine in Bipolar Disorder: A Review</p>
Alina Wilkowska, Łukasz P. Szałach, Wiesław Jerzy Cubała
Abstract
Abstract: Bipolar disorder (BD) is a psychiatric illness associated with high morbidity, mortality and suicide rate. It has neuroprogressive course and a high rate of treatment resistance. Hence, there is an unquestionable need for new BD treatment strategies. Ketamine appears to have rapid antidepressive and antisuicidal effects. Since most of the available studies concern unipolar depression, here we present a novel insight arguing that ketamine might be a promising treatment for bipolar disorder. Keywords: ketamine, bipolar disorder, staging, neuroprogression, treatment resistance
Topics & Concepts
KetamineMedicineBipolar disorderDepression (economics)PsychiatryTreatment-resistant depressionSuicide ratesMajor depressive disorderLithium (medication)Poison controlCognitionSuicide preventionMedical emergencyEconomicsMacroeconomicsTreatment of Major DepressionBipolar Disorder and TreatmentTryptophan and brain disorders