Synergistic activation of p53 by actinomycin D and nutlin-3a is associated with the upregulation of crucial regulators and effectors of innate immunity
Małgorzata Krześniak, Artur Zajkowicz, Agnieszka Gdowicz‐Kłosok, Magdalena Głowala‐Kosińska, Barbara Łasut-Szyszka, Marek Rusin
Topics & Concepts
PyroptosisInnate immune systemCell biologyGene knockdownDownregulation and upregulationBiologyProtein kinase RNLRP1InflammasomeCaspaseCancer researchApoptosisProgrammed cell deathKinaseProtein kinase AImmunologyInflammationGeneImmune systemBiochemistryCyclin-dependent kinase 2Inflammasome and immune disordersinterferon and immune responsesNF-κB Signaling Pathways