Synthesis of a macrocyclic oligomer of pyridylbenzoxazole utilizing dynamic covalent bonds and its unsymmetric conversion
Yuya Hokimoto, Takashi Nakamura
Abstract
A new unsymmetric macrocycle was synthesized by an effective and high yield 3-step synthesis, which was composed of macrocyclization, irreversible conversion, and desymmetrization. The dynamic nature of imine bonds as well as selective conversion based on strain release were utilized. Moreover, the unsymmetric macrocycle formed an interesting bivalve-like 2 : 1 complex with zinc.
Topics & Concepts
OligomerCovalent bondYield (engineering)Dynamic covalent chemistryPolymer chemistryChemistryMaterials scienceCombinatorial chemistryOrganic chemistryMoleculeSupramolecular chemistryMetallurgySupramolecular Chemistry and ComplexesSynthesis and Properties of Aromatic CompoundsMolecular Sensors and Ion Detection