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Emerging Antimicrobial-Resistant High-Risk Klebsiella pneumoniae Clones ST307 and ST147

Gisele Peirano, Liang Chen, Barry N. Kreiswirth, Johann Pitout

2020Antimicrobial Agents and Chemotherapy354 citationsDOIOpen Access PDF

Abstract

There is an enormous global public health burden due to antimicrobial-resistant (AMR) Klebsiella pneumoniae high-risk clones. K. pneumoniae ST307 and ST147 are recent additions to the family of successful clones in the species. Both clones likely emerged in Europe during the early to mid-1990s and, in a relatively short time, became prominent global pathogens, spreading to all continents (with the exception of Antarctica). ST307 and ST147 consist of multiple clades/clusters and are associated with various carbapenemases (i.

Topics & Concepts

Klebsiella pneumoniaeAntimicrobialMicrobiologyKlebsiella infectionsBiologyKlebsiellaVirologyEscherichia coliGeneGeneticsAntibiotic Resistance in BacteriaSalmonella and Campylobacter epidemiologyBacteriophages and microbial interactions