Impact of supine exercise on muscle deoxygenation kinetics heterogeneity: mechanistic insights into slow pulmonary oxygen uptake dynamics
Richie P. Goulding, Dai Okushima, Simon Marwood, David C. Poole, Thomas J. Barstow, Tze‐Huan Lei, Narihiko Kondo, Shunsaku Koga
Abstract
We show that supine exercise causes a greater degree of muscle deoxygenation in both deep and superficial muscle and increases the spatial heterogeneity of muscle deoxygenation. Therefore, this study suggests that any O 2 delivery gradient toward deep versus superficial muscle is insufficient to mitigate impairments in oxidative function in response to reduced whole muscle O 2 delivery. More heterogeneous muscle deoxygenation is associated with slower V̇o 2 kinetics.
Topics & Concepts
DeoxygenationSupine positionKineticsChemistryOxygenOxygen deliveryOxidative phosphorylationInternal medicineBiophysicsAnatomyMedicineBiochemistryBiologyCatalysisQuantum mechanicsOrganic chemistryPhysicsCardiovascular and exercise physiologyMuscle activation and electromyography studiesChronic Obstructive Pulmonary Disease (COPD) Research