A novel time-resolved fluorescent lateral flow immunoassay for quantitative detection of the trauma brain injury biomarker-glial fibrillary acidic protein
Satheesh Natarajan, Jayaraj Joseph
Abstract
A highly sensitive time-resolved fluorescence lateral flow immunoassay (TRF-LFIA) was developed to quantify glial fibrillary acidic protein (GFAP), a trauma brain injury (TBI) biomarker in blood, for the purpose of providing a diagnosis of mild brain injury.
Topics & Concepts
Glial fibrillary acidic proteinBiomarkerTraumatic brain injuryImmunoassayBrain traumaPathologyFluorescenceMedicineChemistryImmunologyBiochemistryAntibodyImmunohistochemistryPhysicsQuantum mechanicsPsychiatryS100 Proteins and AnnexinsTraumatic Brain Injury and Neurovascular DisturbancesOrthopedic Infections and Treatments