In vivo modulation of a dominant‐negative variant in mouse models of von Willebrand disease type 2A
Matteo Campioni, Paulette Legendre, Cécile Loubière, Barbara Lunghi, Mirko Pinotti, Olivier D. Christophe, Peter J. Lenting, Cécile V. Denis, Francesco Bernardi, Caterina Casari
Topics & Concepts
Von Willebrand diseaseIn vivoVon Willebrand factorMutantSmall interfering RNAGene silencingPhenotypeIn vitroWild typeGeneChemistryMolecular biologyRNAGeneticsBiologyImmunologyPlateletPlatelet Disorders and TreatmentsBlood groups and transfusionMyeloproliferative Neoplasms: Diagnosis and Treatment