SIRPA enhances osteosarcoma metastasis by stabilizing SP1 and promoting SLC7A3-mediated arginine uptake
Peng Wang, Yihui Song, Hongyu Li, Jiahao Zhuang, Xin Shen, Wen Yang, Rujia Mi, Yixuan Lu, Biao Yang, Mengjun Ma, Huiyong Shen, Huiyong Shen
Topics & Concepts
Downregulation and upregulationMAPK/ERK pathwayGene knockdownArginineCancer researchOsteosarcomaKinaseCell biologyExtracellularArginasePhosphorylationBiologyCell migrationChemistryCellCell cultureBiochemistryAmino acidGeneGeneticsPhagocytosis and Immune RegulationAdenosine and Purinergic SignalingImmune cells in cancer