New perspectives on traumatic bone infections
Ruohui Tang, Jing Yang, Jun Fei
Abstract
In this paper, we review the results of previous studies and summarize the effects of various factors on the regulation of bone metabolism in traumatic bone infections. Infection-related bone destruction incorporates pathogens and iatrogenic factors in the process of bone resorption dominated by the skeletal and immune systems. The development of bone immunology has established a bridge of communication between the skeletal system and the immune system. Exploring the effects of pathogens, skeletal systems, immune systems, and antibacterials on bone repair in infectious conditions can help improve the treatment of these diseases.
Topics & Concepts
Bone InfectionImmune systemBone resorptionBone remodelingOsteoimmunologyMedicineBone healingImmunologyIntensive care medicineBioinformaticsOsteomyelitisBiologyInternal medicineSurgeryReceptorRANKLActivator (genetics)Orthopedic Infections and TreatmentsOsteomyelitis and Bone Disorders ResearchBone Metabolism and Diseases