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Human microbiota from drug-naive patients with obsessive-compulsive disorder drives behavioral symptoms and neuroinflammation via succinic acid in mice

Ying-Dan Zhang, Dongdong Shi, Bing-Bing Liao, Yi Li, Sen Zhang, Jian Gao, Liangjun Lin, Zhen Wang

2024Molecular Psychiatry27 citationsDOI

Topics & Concepts

NeuroinflammationObsessive compulsiveDrugPsychologyGut floraDrug-naïveSuccinic acidMedicinePharmacologyPsychiatryInflammationImmunologyBiologyBiochemistryTryptophan and brain disordersObsessive-Compulsive Spectrum DisordersGut microbiota and health
Human microbiota from drug-naive patients with obsessive-compulsive disorder drives behavioral symptoms and neuroinflammation via succinic acid in mice | Litcius