Interleukin-1α release during necrotic-like cell death generates myeloid-driven immunosuppression that restricts anti-tumor immunity
Kay Hänggi, Jie Li, Achintyan Gangadharan, Xiaoxian Liu, Daiana P. Celias, Olabisi Osunmakinde, Aysenur Keske, Joshua Davis, Faiz Ahmad, Auriane Giron, Carmen M. Anadon, Alycia Gardner, David G. DeNardo, Timothy I. Shaw, Amer A. Beg, Xiaoqing Yu, Brian Ruffell
Topics & Concepts
ImmunosuppressionMyeloid cellsImmunityMyeloidImmunologyCancer researchProgrammed cell deathBiologyImmune systemMedicineApoptosisBiochemistryImmune Cell Function and InteractionImmunotherapy and Immune ResponsesImmune cells in cancer