Enantioselective synthesis of tryptanthrin derivatives enabled by an asymmetric aza-Friedel–Crafts reaction
Yong You, Guo-Ying Gan, Si-Yang Duan, Yanping Zhang, Qun Li, Zhen‐Hua Wang, Jian‐Qiang Zhao, Xiong‐Li Liu, Wei‐Cheng Yuan
Abstract
A class of ketimines was first prepared and used in an asymmetric aza-Friedel–Crafts reaction for the highly enantioselective synthesis of tryptanthrin derivatives.
Topics & Concepts
Enantioselective synthesisFriedel–Crafts reactionChemistryOrganic chemistryCombinatorial chemistryCatalysisQuinazolinone synthesis and applicationsChemical Synthesis and AnalysisAdvanced Synthetic Organic Chemistry