Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2
Hengyue Shan, Jianping Liu, Jiali Shen, Jialin Dai, Gang Xu, Kuankuan Lu, Chao Han, Yaru Wang, Xiaolong Xu, Yilun Tong, Huaijiang Xiang, Zhiyuan Ai, Guanglei Zhuang, Junhao Hu, Zheng Zhang, Ying Li, Lifeng Pan, Li Tan
Topics & Concepts
PapainProteaseSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakChemistryPharmacologyEnzymeMedicineBiochemistryInternal medicineDiseaseOutbreakInfectious disease (medical specialty)RNA Interference and Gene DeliverySARS-CoV-2 and COVID-19 ResearchCell death mechanisms and regulation