A Mechanism of Action of Metformin in the Brain: Prevention of Methylglyoxal-Induced Glutamatergic Impairment in Acute Hippocampal Slices
Adriana Fernanda K. Vizuete, Fernanda Telles Fróes, Marina Seady, Fernanda Hansen, Rodrigo Ligabue‐Braun, Carlos‐Alberto Gonçalves, Diogo O. Souza
Topics & Concepts
MetforminNeuroprotectionMethylglyoxalGlutamatergicPharmacologyNeurotoxicityGlutamate receptorNeuroinflammationBiguanideAMPA receptorExcitotoxicityEndocrinologyInternal medicineMedicineChemistryInflammationBiochemistryDiabetes mellitusToxicityReceptorEnzymeAdvanced Glycation End Products researchAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms