Association between Angiotensin Blockade and Incidence of Influenza in the United Kingdom
Sheng‐Chia Chung, Rui Providência, Reecha Sofat
Abstract
Certain influenza strains and SARS-CoV-2 gain access to cells by means of the ACE2 receptor. In this database study in the United Kingdom, investigators observed a null-to-protective effect on influenza susceptibility among those taking ACE inhibitors or angiotensin-receptor blockers, possibly owing to mechanisms relevant to infection with coronaviruses, including SARS-CoV-2.
Topics & Concepts
MedicineBlockadeIncidence (geometry)Angiotensin IIInternal medicineReceptorOpticsPhysicsCOVID-19 Clinical Research StudiesInfluenza Virus Research StudiesRenin-Angiotensin System Studies