Label-Free Plasmonic Biosensor for Rapid, Quantitative, and Highly Sensitive COVID-19 Serology: Implementation and Clinical Validation
Olalla Calvo-Lozano, Miquel Sierra‐Montoya, Maria Soler, M.‐Carmen Estévez, Luis Chiscano‐Camón, Adolfo Ruiz-Sanmartín, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Juan José González‐López, Juliana Esperalba, Candela Fernández‐Naval, Leticia Bueno, Rubén López-Aladid, Antoni Torres, Laia Fernández‐Barat, Sarah Attoumani, Rémi N. Charrel, Bruno Coutard, Laura M. Lechuga
Abstract
= 120) demonstrates its excellent diagnostic sensitivity (99%) and specificity (100%). This positions our biosensor as an accurate and easy-to-use diagnostics tool for rapid and reliable COVID-19 serology to be employed both at laboratory and decentralized settings for the disease management and for the evaluation of immunological status during vaccination or treatment.
Topics & Concepts
ChemistryBiosensorCoronavirus disease 2019 (COVID-19)SerologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakChromatographyNanotechnologyVirologyAntibodyBiochemistryImmunologyPathologyInfectious disease (medical specialty)Materials scienceDiseaseMedicineOutbreakBiologySARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testingCOVID-19 Clinical Research Studies