Photo-mediated synthesis of 1,2-dideoxy-2-phosphinylated carbohydrates from glycals: the reduction of glycosyl radicals to glycosyl anions
Li Hai, Kai-Cheng Yu, Jiakun Su, Wei Ouyang, Nai-Li Fan, Xiang‐Guo Hu
Abstract
A metal-free, photo-mediated method for the synthesis of C2-phosphorylated carbohydrates has been developed, whose reaction mechanism consists of the reduction of a glycosyl radical to a glycosyl anion.
Topics & Concepts
GlycosylChemistryRadicalGlycosylationCombinatorial chemistryOrganic chemistryBiochemistryCarbohydrate Chemistry and SynthesisRadical Photochemical ReactionsSulfur-Based Synthesis Techniques