Potentiating the Anti-Tuberculosis Efficacy of Peptide Nucleic Acids through Combinations with Permeabilizing Drugs
Karishma Berta Cotta, Saptarshi Ghosh, Sarika Mehra
Abstract
Peptide nucleic acids have great potential in therapeutics as anti-gene/anti-sense agents. However, their limited uptake in cells has curtailed their widespread application.
Topics & Concepts
INHAPeptide nucleic acidIntracellularNucleic acidExtracellularEthambutolTuberculosisMicrobiologyMycobacterium tuberculosisBiologyPharmacologyBiochemistryChemistryAntibioticsMedicineRifampicinPathologyCancer therapeutics and mechanismsHIV/AIDS drug development and treatmentTuberculosis Research and Epidemiology