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Healthcare AI, explainability, and the human-machine relationship: a (not so) novel practical challenge

Claudia Giorgetti, Giuseppe Contissa, Giuseppe Basile

2025Frontiers in Medicine15 citationsDOIOpen Access PDF

Abstract

This paper focuses on the lack of explainability that afflicts machine-learning-based AI systems applied in the field of healthcare. After a brief introduction to the topic, from both a technical and legal point of view, this work aims to assess the main consequences that the lack of explainability has on the human-machine relationship in clinical care, through a practical perspective. It then questions whether explainability is truly an objective worth seeking and, if so, to what extent, taking into account the current possible solutions.

Topics & Concepts

Perspective (graphical)Health careField (mathematics)Point (geometry)Work (physics)Human healthComputer scienceRisk analysis (engineering)Engineering ethicsData scienceArtificial intelligencePsychologyManagement scienceMedicineEngineeringPolitical scienceMechanical engineeringEnvironmental healthMathematicsPure mathematicsLawGeometryArtificial Intelligence in Healthcare and EducationExplainable Artificial Intelligence (XAI)Ethics in Clinical Research
Healthcare AI, explainability, and the human-machine relationship: a (not so) novel practical challenge | Litcius