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Association of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, mean platelet volume with the risk of gestational diabetes mellitus

Wenhua Liu, Xiangming Lou, Zhifen Zhang, Yun Chai, Qing Yu

2020Gynecological Endocrinology38 citationsDOI

Abstract

OBJECTIVE: In the present study, we aimed to investigate the correlation of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, mean platelet volume with the risk of gestational diabetes mellitus. METHODS: = 62). The NLR, PLR and MPV levels were measured. RESULTS: NLR, PLR and MPV were significantly higher in GDM compared with control group. Logistic regression analysis showed that elevated WBC, NLR, PLR and MPV was an independent variable for predicting GDM in pregnancy. The OR and 95% CI was (OR: 1.6, 95% CI: 1.2-2.5), (OR: 4.1, 95% CI: 1.3-13.1), (OR: 5.5, 95% CI: 1.5-20.0), (OR: 4.0, 95% CI: 1.2-12.0), respectively. CONCLUSION: Increased WBC, PLR, NLR, MPV were independent predictors of GDM.

Topics & Concepts

Mean platelet volumeMedicineGestational diabetesInternal medicineDiabetes mellitusPlateletLogistic regressionNeutrophil to lymphocyte ratioGastroenterologyLymphocytePregnancyGestationImmunologyEndocrinologyBiologyGeneticsInflammatory Biomarkers in Disease PrognosisPregnancy and preeclampsia studiesGestational Diabetes Research and Management
Association of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, mean platelet volume with the risk of gestational diabetes mellitus | Litcius