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Dual-light defined <i>in situ</i> oral mucosal lesion therapy through a mode switchable anti-bacterial and anti-inflammatory mucoadhesive hydrogel

Huijie Liu, Qun Li, Yingying Xu, Yue Sun, Xinxiang Fan, Huaqiang Fang, Binbin Hu, Li Huang, Lan Liao, Xiaolei Wang

2023Biomaterials Science25 citationsDOI

Abstract

ZPTA-G/HMA can treat oral mucosal lesions by in situ anchoring to wet mucosa surface for hemostasis and the production of ROS for anti-bacteria under GL irradiation, as well as by enhanced anti-inflammation for promoting healing with NIR irradiation.

Topics & Concepts

Oral mucosaIn vivoPhotothermal therapySelf-healing hydrogelsChemistryHyaluronic acidGelatinMaterials scienceMedicinePolymer chemistryPathologyBiochemistryNanotechnologyBiologyAnatomyBiotechnologyCorneal Surgery and TreatmentsLaser Applications in Dentistry and MedicinePeriodontal Regeneration and Treatments
Dual-light defined <i>in situ</i> oral mucosal lesion therapy through a mode switchable anti-bacterial and anti-inflammatory mucoadhesive hydrogel | Litcius