A water-soluble pyrazino[2,3-<i>g</i>]quinoxaline photosensitizer for high-efficiency one- and two-photon excited bioimaging and photodynamic therapy
Lipeng Zhang, Xianqiang Li, Tianlong Liu, Lin Kang, Xing Huang, Yuxia Zhao
Abstract
, 5 min) or two-photon excitation (2PE) of an 820 nm fs laser (100 mW, 80 MHz, 140 fs, 5 min), PQs-PEG5 (10 μM) could cause HeLa and 4T1 cell death effectively, which indicated its great potential as a novel photosensitizer for both 1PE- and 2PE-PDT applications.
Topics & Concepts
PhotosensitizerQuinoxalinePhotodynamic therapyExcited statePhotochemistryChemistryPhotonPhysicsOpticsOrganic chemistryAtomic physicsNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesLuminescence and Fluorescent Materials