Synthesis, biological evaluation of novel thiopyrano[2,3-d]thiazoles incorporating arylsulfonate moiety as potential inhibitors of tubulin polymerization, and molecular modeling studies
Nadia H. Metwally, Mohamed A. Badawy, Doha Samir Okpy
Topics & Concepts
ChemistryHeLaMoietyStereochemistryCytotoxicityDoxorubicinIC50ThiazoleTubulinCell cultureMicrotubuleCellBiochemistryIn vitroChemotherapyBiologyCell biologySurgeryMedicineGeneticsSynthesis and biological activityClick Chemistry and ApplicationsSynthesis and Characterization of Heterocyclic Compounds