Understanding the nanoscale adhesion forces between the fungal pathogen <i>Candida albicans</i> and antimicrobial zinc-based layered double hydroxides using single-cell and single-particle force spectroscopy
Jazia Awassa, Samantha Soulé, Damien Cornu, Christian Ruby, Sofiane El‐Kirat‐Chatel
Abstract
ZnAl LDH NPs showed remarkable antifungal properties against C. albicans fungal cells. The antifungal activity was linked to the adhesion-specific interactions between ZnAl nanoparticles and C. albicans , which were probed by both SPFS and SCFS.
Topics & Concepts
Candida albicansCorpus albicansForce spectroscopyAdhesionAntifungalAntimicrobialNanoscopic scaleZincAtomic force microscopyMicrobiologyChemistryMaterials scienceFungal pathogenCell adhesionNanoparticleNanotechnologyPathogenBiophysicsBiologyComposite materialOrganic chemistryLayered Double Hydroxides Synthesis and ApplicationsPolymer Surface Interaction StudiesBone Tissue Engineering Materials