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Sustained effects of rapidly acting antidepressants require BDNF-dependent MeCP2 phosphorylation

Ji‐Woon Kim, Anita E. Autry, Elisa S. Na, Megumi Adachi, Carl Björkholm, Ege T. Kavalali, Lisa M. Monteggia

2021Nature Neuroscience109 citationsDOIOpen Access PDF

Topics & Concepts

AntidepressantMECP2KetamineNeuroscienceSynaptic plasticityPharmacologyNMDA receptorMedicineHippocampusPsychologyBiologyInternal medicinePhenotypeReceptorGeneBiochemistryNeuroscience and Neuropharmacology ResearchTreatment of Major DepressionTryptophan and brain disorders
Sustained effects of rapidly acting antidepressants require BDNF-dependent MeCP2 phosphorylation | Litcius