Downregulation of Interferon-γ Receptor Expression Endows Resistance to Anti–Programmed Death Protein 1 Therapy in Colorectal Cancer
Chunxiao Lv, Dongfen Yuan, Yanguang Cao
Topics & Concepts
Immune checkpointCancer researchDownregulation and upregulationSmall hairpin RNAGene knockdownImmune systemCancerImmunotherapyPD-L1InterferonColorectal cancerBiologyMedicineCell cultureImmunologyInternal medicineBiochemistryGeneGeneticsCancer Immunotherapy and BiomarkersImmune Cell Function and InteractionColorectal Cancer Treatments and Studies