Recent advances in biomimetic hemostatic materials
Simin Jiao, Xi Zhang, Hang Cai, Siyu Wu, Xiaolan Ou, Guangda Han, Jie Zhao, Yan Li, Wenlai Guo, Tianzhou Liu, Wenrui Qu
Abstract
Although the past decade has witnessed unprecedented medical advances, achieving rapid and effective hemostasis remains challenging. Uncontrolled bleeding and wound infections continue to plague healthcare providers, increasing the risk of death. Various types of hemostatic materials are nowadays used during clinical practice but have many limitations, including poor biocompatibility, toxicity and biodegradability. Recently, there has been a burgeoning interest in organisms that stick to objects or produce sticky substances. Indeed, applying biological adhesion properties to hemostatic materials remains an interesting approach. This paper reviews the biological behavior, bionics, and mechanisms related to hemostasis. Furthermore, this paper covers the benefits, challenges and prospects of biomimetic hemostatic materials.