Single-cell multi-omics profiling of human preimplantation embryos identifies cytoskeletal defects during embryonic arrest
T. Q. Wang, Junhua Peng, Jiaqi Fan, Ni Tang, Rui Hua, Xueliang Zhou, Zhihao Wang, Longfei Wang, Yanling Bai, X. Quan, Zimeng Wang, Li Zhang, Chen Luo, Weiqing Zhang, Xiangjin Kang, Jianqiao Liu, Lei Li, Lin Li
Topics & Concepts
BiologyReprogrammingTranscriptomeCell biologyMaternal to zygotic transitionEmbryonic stem cellChromatinEpigeneticsDNA methylationGeneticsEpigenomeEpigenomicsGenome instabilityDNA damageEmbryoZygoteEmbryogenesisGeneGene expressionDNAEpigenetics and DNA MethylationPluripotent Stem Cells ResearchCRISPR and Genetic Engineering